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Department of Toxicology

Department of Toxicology

Toxicology is the science that investigate the adverse effects of chemicals on living organisms (negative, adverse), and that has existed since ancient times, developing and predictive property. It is a multidisciplinary science that determine in living beings that are exposed to physical, chemical and biological agents (substances), the toxic effects that may occur after exposure and which mechanisms of the toxic effects occur (toxic mechanisms) and how to protect against the toxic effects occurring (antidotes), the credibility ranges for chemicals. Toxicology has subdivisions such as clinical toxicology, environmental toxicology, molecular toxicology, analytical toxicology and occupational toxicology.

Depending on the rapid development of industry and technology, people are exposed to many toxic substances in both daily life and workplaces. Nowadays, there are approximately 70 thousand chemicals, including majority synthetic chemicals and new chemical substances enter the human life every year. Thus, the importance of toxicology as a science which determines the threshold limits for chemicals is increasing day by day.

Our department has two laboratory for research and education purposes. At the our department, it is done studies on genetic polymorphisms, molecular toxicology, analytical toxicology, forensic toxicology, genetic toxicology, environmental toxicology. Our graduate program is carried on by collaboration with Gazi University and Mersin University.


Publications in International Scientific Journals(last two years)

2021
14. Battal, D.; Aktaş şüküroğlu, A.; Kocadal, K.; ünlüsayın, .; çok, .; ünlüsayın, . Establishment of rapid, sensitive, and quantitative liquid chromatography-electrospray ionization-tandem mass spectrometry method coupled with liquid-liquid extraction for measurement of urinary bisphenol A, 4-t-octylphenol, and 4-nonylphenol. RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 2021, 35, ---.
10.1002/rcm.9084
13. Battal, D.; Sukuroglu, A.; Kocadal, K.; Unlusayin, I.; çok, I. Establishment of rapid, sensitive, and quantitative LC‐ESI‐MS/MS method coupled with liquid‐liquid extraction for measurement of urinary bisphenol A, 4‐t‐octylphenol, and 4‐nonylphenol. RAPID COMMUNICATION IN MASS SPECTROMETRY, 2021, 0, 0-0.
http://doi.org/10.1002/rcm.9084
12. Kocadal, K.; Alkaş, F.; Ulutaş, O.; Kurt, M.; Battal, D.; şardaş, S.; Etikan, .; Saygı, . Biomonitoring of Heavy Metal(oid)s in the Residents of Abandoned Mining District in Northern Cyprus. BIOLOGICAL TRACE ELEMENT RESEARCH, 2021, 1, 1-10.
https://doi.org/10.1007/s12011-020-02520-1
11. Njoh, R.; Kocadal, K.; Alkaş, F.; Kurt, M.; Battal, D.; Saygı, . HEAVY METAL POLLUTION OF AGRICULTURAL SOILS AND VEGETABLES OF ABANDONED MINING DISTRICT IN NORTHERN CYPRUS . FRESENIUS ENVIRONMENTAL BULLETIN, 2021, 30, 1415-1423.
Publications_012.pdf
2020
10. Uckun, Z.; Güzel, S.; Canacankatan, N.; Yalaza, C.; Kibar, D.; Coskun yilmaz, B. Potential protective effects of naringenin against vancomycin-induced nephrotoxicity via reduction on apoptotic and oxidative stress markers in rats.. DRUG AND CHEMICAL TOXICOLOGY, 2020, 43, 104-111.
doi: 10.1080/01480545.2018.1512612
9. Alas, M.; Alkas, B.; Aktaş şüküroğlu, A.; Genç altürk, R.; Battal, D. . JOURNAL OF MATERIALS SCIENCE, 2020, 55, 15074-15105.
8. Kocadal, K.; Alkas, B.; Battal, D.; Saygı, . . HUMAN EXPERIMENTAL TOXICOLOGY, 2020, 39, 3-13.
7. Oz, M.; Baskak, B.; Uckun, Z.; Artun, N.; Ozdemir, H.; Ozel, T.; Ozguven, H.; Suzen, H. Association between serotonin 2A receptor (HTR2A), serotonin transporter (SLC6A4) and brain-derived neurotrophic factor (BDNF) gene polymorphisms and citalopram/sertraline induced sexual dysfunction in MDD patients. PHARMACOGENOMICS J, 2020, 20, 443-450.
http://dx.doi.org/10.1038/s41397-019-0127-8
6. Guzel, S.; Uckun , Z.; Canacankatan, N.; Antmen, S.; Kibar, D.; Coskun yilmaz, B. Potential renoprotective effects of silymarin against vancomycin-induced nephrotoxicity in rats. DRUG CHEM TOXICOL, 2020, 43, 630-636.
http://dx.doi.org/10.1080/01480545.2019.1584208
5. çok, .; Toprak ikidağ, O.; Battal, D.; Aktaş şüküroğlu, A. . JOURNAL OF CLINICAL RESEARCH IN PEDIATRIC ENDOCRINOLOGY, 2020, 12, 86-94.
10.4274/jcrpe.galenos.2019.2019.0087
4. şimşek, S.; Aktaş şüküroğlu, A.; Yetkin, D.; özbek, B.; Battal, D.; Genç altürk, R. . SCIENTIFIC REPORTS, 2020, 10, -.
10.1038/s41598-020-70796-3
3. çok, .; Toprak, .; Battal, D.; Aktaş şüküroğlu, A. . JOURNAL OF CLINICAL RESEARCH IN PEDIATRIC ENDOCRINOLOGY, 2020, 12, -.
2. Akgönüllü, S.; Battal, D.; Yalçın, M.; Yavuz alagöz, H.; Denizli, A. . MICROCHEMICAL JOURNAL, 2020, 153, -.
1. Alas, M.; Alkaş, F.; Aktaş şüküroğlu, A.; Genç altürk, R.; Battal, D. . JOURNAL OF MATERIALS SCIENCE, 2020, 55, -.
10.1007/s10853-020-05054-y