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Department of Biochemistry

Department of Biochemistry

The purpose of biochemistry is to investigate biochemical events in living cells at molecular level. With this aim, structure and metabolism of macromoleculs and regulation of hormonal and enzymatic are taught. Our department provides training since the Faculty of Pharmacy founded. Education at the undergraduate and graduate levels is carried out by 1 professor, 2 associate professors, 1 assistant professors and 1 research assistant  worked in our department. Our undergraduate courses include Biochemistry, Clinical Biochemistry, Nutritional Biochemistry, Antioxidants and Free Radicals, Biochemical Laboratory Data. The emphasis of our graduate program is on comprehensive research training in our laboratories and also several courses are given about advanced biochemistry, metabolism diseases, signalling patways, hormones, proteins, lipoproteins and recombinant DNA techniques. The objectives of the master and doctorate programs are to provide and develop basic knowledge and laboratory skills in the field of biochemistry and Health Sciences. Our major research facilities include enzymology, oxidative stress, apoptosis, protein chemistry, hemoglobinopathies and molecular biology.


Publications in International Scientific Journals(last two years)

2021
14. özdemir, E.; çömelekoğlu, .; Degirmenci, E.; Bayrak, G.; Yildirim, M.; Ergenoglu, T.; Coşkun yılmaz, B.; Korunur engiz, B.; Yalin, S. The effect of 4.5 G (LTE Advanced-Pro network) mobile phone radiation on the optic nerve. INFORMA UK LIMITED, 2021, 40, 198-206.
http://dx.doi.org/10.1080/15569527.2021.1895825
13. Gungor, M.; Kurutas, E.; Oner, E.; Unsal, V.; Altun, H.; Yalin, A.; Yalin, S.; Bozkus, O.; Sahin, N. Diagnostic Performance of Erythropoietin and Erythropoietin Receptors Levels in Children with Attention Deficit Hyperactivity Disorder. KOREAN COLLEGE OF NEUROPSYCHOPHARMACOLOGY, 2021, 19, 530-536.
http://dx.doi.org/10.9758/cpn.2021.19.3.530
12. Efsun antmen, S.; Canacankatan, N.; Gürses, .; Aytan, H.; Erden ertürk, S. Relevance of lipogenesis and AMPK/Akt/mTOR signaling pathway in endometrial cancer. EUR REV MED PHARMACOL SCI , 2021, 25, 687-695.
https://doi.org/10.26355/eurrev_202101_24630
2020
11. Uckun, Z.; Guzel, S.; Canacankatan, N.; Yalaza, C.; Kibar, D.; Coskun yilmaz, B. Potential protective effects of naringenin against vancomycin-induced nephrotoxicity via reduction on apoptotic and oxidative stress markers in rats. DRUG CHEM TOXICOL., 2020, 43, 104-111.
http://dx.doi.org/10.1080/01480545.2018.1512612
10. Arpaci, A.; Yalın, S.; Ecevit, H.; Comelekoglu, U.; Mete, T. Enzyme activity and genetic polymorphisms in patients with type II diabetes mellitus. WROCLAW MEDICAL UNIVERSITY, 2020, 29, 1057-1063.
http://dx.doi.org/10.17219/acem/125397
9. Yalaza, C.; Canacankatan, N.; Gürses, .; Aytan, H.; Taşdelen, B. Altered VEGF, Bcl-2 and IDH1 expression in patients with adenomyosis. ARCH GYNECOL OBSTET., 2020, 302, 1221-1227.
http://dx.doi.org/10.1007/s00404-020-05742-9
8. Berköz, M.; Yıldırım, M.; Yalın, S.; Ilhan, M.; Yunusoğlu, O. Myricetin inhibits angiotensin converting enzyme and induces nitric oxide production in HUVEC cell line. AEPRESS, S.R.O., 2020, 39, 249-258.
http://dx.doi.org/10.4149/gpb_2020007
7. Erşatır, M.; Yıldırım, M.; Giray, E.; Yalın, S. Synthesis and antiproliferative evaluation of novel biheterocycles based on coumarin and 2-aminoselenophene-3-carbonitrile unit. SPRINGER SCIENCE AND BUSINESS MEDIA LLC, 2020, 151, 625-636.
http://dx.doi.org/10.1007/s00706-020-02573-x
6. Guzel, S.; Sahinogullari, Z.; Canacankatan, N.; Antmen, S.; Kibar, D.; Coskun yilmaz, B. Potential renoprotective effects of silymarin against vancomycin-induced nephrotoxicity in rats. DRUG CHEM TOXICOL, 2020, 43, 630-636.
http://dx.doi.org/10.1080/01480545.2019.1584208
5. Barlaz us, S.; Vezir, O.; Yildirim, M.; Bayrak, G.; Yalin, S.; Balli, E.; Yalin, A.; çömelekoğlu, . Protective effect of N-acetyl cysteine against radiotherapy-induced cardiac damage. INFORMA UK LIMITED, 2020, 96, 661-670.
http://dx.doi.org/10.1080/09553002.2020.1721605
2019
4. Eras, N.; Türkoz, G.; Tombak, A.; Tiftik, E.; Yalın, S.; Berkoz, M.; Erden, S.; Akbaş, E. . ARCHIVES OF MEDICAL SCIENCE, 2019, , 1-6.
89692
3. Berköz, M.; özkan yılmaz, F.; özlüer hunt, A.; Gündüz, S.; Yıldırım, M.; Yalın, S. . FRESENIUS ENVIRONMENTAL BULLETIN, 2019, 28, 4642-4649.
2. Barlaz us, S.; Söğüt, F.; Yıldırım, M.; Yetkin, D.; Yalın, S.; Yılmaz, N.; çömelekoğlu, . . CANCER INVESTIGATION, 2019, 37, 489-500.
10.1080/07357907.2019.1662434
1. çelik, A.; Güler, G.; Aktaş, C.; Yalın, S. . BIOMARKERS, 2019, 24, 720-725.
10.1080/1354750X.2019.1658804